Translational Research in Malignancies Members
The Translational Research in Malignancies (TRIM) program is a highly interactive translational cancer research program. Its main objective is to conduct studies centered on molecular mechanisms of cancer progression and therapeutic resistance and to translate basic science and preclinical discoveries into early diagnosis, biomarkers, and cancer therapeutics.
Dmello, Crismita
Research Assistant Professor
Bio
My central hypothesis is that glioma cell-specific Chek2-YBX1/3 interaction transcriptionally reprograms the glioma cells to escape the CD8 T cell mediated killing.
Eckerdt, Frank
Research Associate Professor
Bio
The goal of my research is to define and target signaling networks promoting resistance mechanisms in cancer stem cells (CSCs) of the brain. Brain cancers are heterogeneous tumors, exhibitin... [more]
Eklund, Elizabeth A.
Professor
Bio
The focus of my laboratory is to understand the key events in normal myelopoiesis and how leukemia-associated mutations derange these processes during leukemogenesis.
Godley, Lucy
Professor
Bio
The Godley laboratory studies the molecular pathways that drive hematopoietic malignancies, with a focus on understanding how germline predisposition alleles contribute to individual and family risk a... [more]
Gordon, Leo I.
Professor
Bio
Novel signaling pathways in lymphoma, using cell lines and animal model systems. More specifically, our research focuses on the biology of reactive oxygen species signaling pathways in lymphoma. Activ... [more]
Gradishar, William J.
Professor
Bio
My research focuses on the development of novel therapeutics for the treatment of breast cancer.
Guitart, Joan
Professor
Bio
Cutaneous T-cell lymphoma, Dermatopathology, Skin cancer prevention and detection.
Heimberger, Amy
Professor
Bio
I am a physician-scientist and a board-certified Neurosurgeon with extensive training and experience in the field of immunology. My laboratory is focused on elucidating the mechanisms of tumor-mediate... [more]
Hines, Jacobi
Assistant Professor
Bio
Clinical research/trials, personalized medicine, pharmacogenomics
Horbinski, Craig
Professor
Bio
My career as a physician-scientist and investigative neuropathologist allows me to conduct research that will enhance our understanding of how key driver mutations, like mutant IDH1, affect glioma bio... [more]